Resumo Introdução Na Odontologia, as resinas são utilizadas como materiais restauradores, para o restabelecimento da estética, da função e da forma dos dentes. Objetivo Avaliar in vitro a microdureza das resinas Filtek Z350 XT® e Filtek Z250 XT®, submetidas ao contato direto quando expostas a colutórios. Material e método Dez corpos de prova foram confeccionados em uma matriz de náilon, em dois incrementos, e foram fotoativados por 20 s. A homogeneidade da amostra foi verificada através dos testes Mann-Whitney e Kruskal-Wallis, e uma variância paramétrica foi realizada (ANOVA) para a análise de significância, aplicando-se o teste de Tukey a fim de comparar os resultados (α=5%). Resultado O maior valor médio foi apresentado pelo grupo G1 (Filtek Z350 XT- água destilada- controle) – 138,22(±21,8) e os menores valores foram do grupo G9 (Filtek Z250 XT- Solução de Camomila) – 87,12(±4,39) e do grupo G10 (Filtek Z250 XT- Solução de Romã) – 99,32(±11,10). A resina Filtek Z350 XT foi superior à resina Filtek Z250 XT (p=0,015). Conclusão A resina Filtek Z350 XT apresentou melhores resultados quando estes foram comparados aos resultados da Filtek Z250 XT.

Abstract Introduction In dentistry, resins are used as restorative materials for the reconstruction of aesthetics, function and shape of teeth. Aim To evaluate in vitro the microhardness of Filtek Z350 XT® and Filtek Z250 XT® resins subjected to direct contact when exposed to mouthwashes. Material and method Ten specimens were prepared in a nylon matrix in two increments and photoactivated for 20s. The homogeneity of the sample was verified through the Mann-Whitney and Kruskal-Wallis tests and a parametric variance was performed (ANOVA), and for Tukey significance analysis (α=5%). Result The highest mean value was presented by group G1 (Filtek Z350 XT- distilled water- control) – 138.22 (±21.8), and the least values were from group G9 (Filtek Z250 XT- Chamomile Solution) – 87.12 (±4.39) and the G10 group (Filtek Z250 XT – Pomegranate solution) – 99.32 (±11.10). Filtek Z350 XT resin was superior to Filtek Z250 XT (p=0.015). Conclusion Filtek Z350 XT resin presented better results than Filtek Z250 XT.

Abstract The aim of this study was to evaluate the immunoexpression of glucose transporters 1 (GLUT-1) and 3 (GLUT-3) in keratocystic odontogenic tumors associated with Gorlin syndrome (SKOTs) and non-syndromic keratocystic odontogenic tumors (NSKOTs), and to establish correlations with the angiogenic index. Seventeen primary NSKOTs, seven recurrent NSKOTs, and 17 SKOTs were selected for the study. The percentage of immunopositive cells for GLUT-1 and GLUT-3 in the epithelial component of the tumors was assessed. The angiogenic index was determined by microvessel count. The results were analyzed statistically using the nonparametric Kruskal-Wallis test and Spearman’s correlation test. High epithelial immunoexpression of GLUT-1 was observed in most tumors (p = 0.360). There was a higher frequency of negative cases for GLUT-3 in all groups. The few GLUT-3-positive tumors exhibited low expression of this protein in epithelial cells. No significant difference in the angiogenic index was observed between groups (p = 0.778). GLUT-1 expression did not correlate significantly with the angiogenic index (p > 0.05). The results suggest that the more aggressive biological behavior of SKOTs when compared to NSKOTs may not be related to GLUT-1 or GLUT-3 expression. GLUT-1 may play an important role in glucose uptake by epithelial cells of KOTs and this process is unlikely related to the angiogenic index. GLUT-1 could be a potential target for future development of therapeutic strategies for KOTs.